Cefpiramide Sodium: Full Drug Profile
Cefpiramide Sodium - General Information
Cefpiramide Sodium is a third-generation cephalosporin antibiotic.
Pharmacology of Cefpiramide Sodium
Cefpiramide Sodium is a cephalosporin active against Pseudomonas aeruginosa. It has a broad spectrum of antibacterial activity. Cefpiramide Sodium works by inhibiting bacterial cell wall biosynthesis. The plasma half-lives of cefpiramide in rabbits, dogs, and rhesus monkeys were much longer than those of cefoperazone and cefazolin.
Additional information about Cefpiramide Sodium
Cefpiramide Sodium Indication: For treatment of severe infections caused by susceptible bacteria. Mechanism Of Action: The bactericidal activity of cefpiramide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Cefpiramide Synonyms: Not Available Drug Category: Anti-Bacterial Agents Drug Type: Small Molecule; Approved Other Brand Names containing Cefpiramide: Cefpiramide Sodium; Cefpiramide [USAN-INN]; Cefpiramido [INN-Spanish]; Cefpiramidum [INN-Latin]; Absorption: Rapidly absorbed following intramuscular injection. Toxicity (Overdose): Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions. Protein Binding: Not Available Biotransformation: Not Available Half Life: 4.44 hours Dosage Forms of Cefpiramide Sodium: Not Available Chemical IUPAC Name: (6R)-7-[[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical Formula: C25H24N8O7S2 Cefpiramide on Wikipedia: https://en.wikipedia.org/wiki/Cefpiramide Organisms Affected: Enteric bacteria and other eubacteria